Antioxidant Effect of Lactobacillus acidophilus as a Probiotic at Different Time Intervals‏


Background: Probiotics are survival microorganisms that, when administered in sufficient amounts, confer health benefits to the host and can be used in an antioxidative role.

Objectives: The antioxidative effect of whole cells and intracellular cell-free extracts of the lactic acid bacteria Lactobacillus acidophilus (PTCC 1643) as a probiotic‎ at three different time intervals was investigated.

Materials and Methods: Antioxidant biomarkers, such as total antioxidant power (TAP), measured with the FRAP (ferric-reducing ability of plasma) method, were evaluated at 24, 48, and 72 hours.

Results: The results showed that extracts and bacteria of L. acidophilus were able to significantly increase TAP after 24 and 72 hours.

Conclusions: The results showed that the effect of L. acidophilus is time-dependent.